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Notably, microbial imprinting in the respiratory epithelium may dynamically regulate future immune responses by modulating cytokine output such as IL-1b and IL-8 (149), resembling the trained immunity seen in macrophages

Autosomal recessive congenital sensorineural hearing loss due to a novel compound heterozygous PTPRQ mutation in a Chinese family

Injection-site and quality-control risk Reported injection-site issues include redness, mild swelling, transient bruising, and occasional sterile abscess

Philosophical Trans Royal Soc B: Biol Sci 367(1595)

Biowaivers: In certain cases, such as highly soluble, high-permeability drugs, an in vivo BE study may be waived, relying on in vitro dissolution testing instead